FARXIGA PI PDF
Get dosing information on FARXIGA® (dapagliflozin), for the treatment of type 2 diabetes mellitus. Visit for more. Forxiga is indicated in adults aged 18 years and older with type 2 diabetes Forxiga can be taken orally once daily at any time of day with or without food. FORXIGA® is a registered trademark of AstraZeneca AB, used under . Monotherapy: FORXIGA (dapagliflozin) is indicated for use as an.
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SAVINGS TO KEEP PATIENTS ON QTERN
You may fafxiga side effects related to AstraZeneca products by clicking here. You may report side effects related to AstraZeneca products by clicking here. Use caution in patients with renal transplantation or moderate renal impairment Gastrointestinal Disease Because exenatide is commonly associated with gastrointestinal adverse reactions, not recommended in patients with severe gastrointestinal disease eg, gastroparesis Immunogenicity Patients may develop antibodies to exenatide.
Dapagliflozin causes intravascular volume contraction and symptomatic hypotension can occur. Centers for Disease Control and Prevention. Long-term efficacy of dapagliflozin in patients with type 2 diabetes mellitus receiving high doses of insulin: If you have any of these symptoms, stop taking FARXIGA and contact your healthcare provider or go to the nearest hospital emergency room right away have severe kidney problems or are on dialysis.
Randomized, double-blind, phase 3 trial of triple therapy with dapagliflozin add-on to saxagliptin plus metformin in type 2 diabetes.
Consider temporarily discontinuing in settings of reduced oral intake or fluid losses. Consider other antidiabetic therapies in patients with a history of pancreatitis Hypoglycemia Risk of hypoglycemia is increased pj exenatide is coadministered with insulin or insulin secretagogues.
Use with caution in patients with a history of bladder cancer Severe and Disabling Arthralgia has been reported in patients taking DPP-4 inhibitors.
Accessed September 28, AstraZeneca Pharmaceuticals LP; Warnings and Precautions Pancreatitis: An imbalance in bladder cancers was observed in clinical trials.
Seek medical attention immediately if you have fever or you are feeling very weak, tired or uncomfortable and you also develop any pain or tenderness, swelling, or redness of the skin in the genitals and areas around them Vaginal yeast infections in women who take FARXIGA.
After initiation, observe patients carefully for symptoms of pancreatitis. Monitor for ffarxiga and symptoms.
Assess patients who present with signs and symptoms of metabolic acidosis for ketoacidosis, regardless of blood glucose level. Dapagliflozin improves muscle insulin sensitivity but enhances endogenous glucose production. Long-term glycaemic response and tolerability of dapagliflozin versus a sulphonylurea as add-on therapy to metformin in patients with type 2 diabetes: Exenatide once weekly plus dapagliflozin once daily versus exenatide or dapagliflozin alone in patients with type 2 diabetes inadequately controlled with metformin monotherapy DURATION Not recommended in patients with severe renal impairment or end-stage renal disease.
Ketoacidosis is a serious condition which may farxigga hospitalization and ;i lead to death.
Dosing Information for FARXIGA® (dapagliflozin)
Age-adjusted percentage of adults aged 18 years or older with diagnosed diabetes who were overweight, United States, — If farxita of or failure to achieve adequate glycemic control occurs, consider alternative antidiabetic therapy Hypersensitivity Reports of serious hypersensitivity reactions eg, anaphylaxis and angioedema.
Evaluate for signs and symptoms of UTIs and treat promptly Hypoglycemia: Rare but serious infections that cause severe tissue damage under the skin of the genitals and areas around them have happened with FARXIGA.
FARXIGA is a prescription medicine used along with diet and exercise to lower blood sugar in adults with type 2 diabetes. Not available for government-insured patients. An imbalance in bladder cancers was observed in clinical trials. Evaluate for signs farxkga symptoms of UTIs and treat promptly. Rare but serious, life-threatening cases have been reported in patients receiving SGLT2 inhibitors including dapagliflozin. If acute kidney injury occurs, discontinue and promptly treat Dapagliflozin increases serum creatinine and decreases eGFR.
Effect of dapagliflozin in patients farxlga type 2 diabetes who have inadequate glycaemic control with metformin: The pill that starts with. Dapagliflozin causes intravascular volume contraction and renal impairment, with reports of acute kidney injury requiring farxigs and dialysis.
Serious outcomes have included hospitalization, surgeries, and death. The time to onset of symptoms following initiation of drug therapy varied from one day to years.
Advise females of potential risk to a fetus especially during the second and third trimesters Lactation: Symptoms may include nausea, tiredness, vomiting, trouble breathing, and abdominal pain. Farxigw and correct volume status before initiating FARXIGA ffarxiga patients with impaired renal function, elderly patients, or patients on loop diuretics.
FARXIGA® (dapagliflozin) | Type 2 Diabetes Medication for Adults
Talk to your healthcare provider if you experience vaginal odor, white or yellowish vaginal discharge discharge may be lumpy or look like cottage cheeseor vaginal itching Yeast infection of skin around the penis balanitis in men who take FARXIGA. You may report side effects related to AstraZeneca products by clicking here. Estimates of diabetes and its burden in the United States, Tell your doctor if you have any signs or symptoms of UTI including a burning feeling when passing urine, a need to urinate often, the need to urinate right away, pain in the lower part of your stomach pelvisor blood in the urine with or without fever, back pain, nausea, or vomiting Low blood sugar hypoglycemia can occur if you take FARXIGA with another medicine that can cause low blood sugar, such as sulfonylureas or insulin.
There have been postmarketing reports of bullous pemphigoid requiring hospitalization in patients taking DPP-4 inhibitors. Patients experienced relief of symptoms upon discontinuation.
Use caution in patients with a history of angioedema to another DPP-4 inhibitor. Symptoms of low blood sugar include shaking, sweating, fast heartbeat, dizziness, hunger, headache, and irritability. farziga